Professor
Department of Mechanical Engineering
Whiting School of Engineering
B.S., B.A., M.S.E. 1988, Johns Hopkins University
Ph.D. 1992, California Institute of Technology
gregc@jhu.edu 117 CSEB
3400 N. Charles Street
Baltimore, MD 21218 Office: 410-516-7127 | - Computational structural biology (in particular, computational mechanics of large proteins)
- Conformational statistics of biological macromolecules
- Developed theory for 'hyper-redundant' (snakelike) robot motion planning
- Designs and builds hyper-redundant robotic manipulator arms
- Applied mathematics (applications of group theory in engineering)
- Self-replicating robotic systems
Selected Publications
Wolfe, K.C., and G.S. Chirikjian. (2012) Quantitative comparison of conformational ensembles. Entropy 14:213-232. Chirikjian, G.S. (2011) Modeling loop entropy. Methods Enzymol. Part C: 487:101-130. Chirikjian, G.S. (2010) Group theory and biomolecular conformation, l.: Mathematical and computational models. J. Phys. Condens. Matter 22:323103. Schuyler, A.D., R.L. Jernigan, P.K. Qasba, B. Ramakrishnan, and G.S. Chirikjian. (2009) Iterative cluster-NMA (icNMA): A tool for generating conformational transitions in proteins. Proteins 74:760-776. Chirikjian, G.S. (2008) The stochastic elastica and excluded-volume perturbations of DNA. Int. J. Non. Mech. 43:1108-1120. Jeong, J., E. Lattman, and G.S. Chirikjian. (2006) A method for finding candidate conformations for molecular replacement using relative rotation between domains of a known structure. Acta Crstallographica D D62:398-409. Zhou, Y., and G.S. Chirikjian. (2006) Conformational statistics of semi-flexible macromolecular chains with internal joints. Macromolecules 39:1950-1960. Lee, S., and G.S. Chirikjian. (2004) Interhelical angle and distance preferences in globular proteins. Biophys. J. 286:1105-17. Kim, M.K., R.L. Jernigan, and G.S. Chirikjian. (2003) An elastic network model of HK97 capsid maturation. J. Struct. Biol. 143:107-117.
Kim, M.K., R.L. Jernigan, and G.S. Chirikjian. (2002) Efficient generation of feasible pathways for protein conformational transitions. Biophys. J. 83:1620-30.
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