Professor
Department of Mechanical Engineering
Whiting School of Engineering

gregc@jhu.edu

117 CSEB
3400 N. Charles Street
Baltimore, MD 21218

Office: 410-516-7127

• Computational structural biology (in particular, computational mechanics of large proteins)
• Conformational statistics of biological macromolecules
• Developed theory for 'hyper-redundant' (snakelike) robot motion planning
•  Designs and builds hyper-redundant robotic manipulator arms
•  Applied mathematics (applications of group theory in engineering)
•  Self-replicating robotic systems

Selected Publications
Skliros, A., and G.S. Chirikjian. (2007) Torsional random-walk statistics on lattices using convolution on crystallographic motion groups. Polymer 48:2155-2173.

Jeong, J., E. Lattman, and G.S. Chirikjian. (2006) A method for finding candidate conformations for molecular replacement using relative rotation between domains of a known structure. Acta Crstallographica D D62:398-409.

Zhou, Y., and G.S. Chirikjian. (2006) Conformational statistics of semi-flexible macromolecular chains with internal joints. Macromolecules 39:1950-1960.

Hastings, W.A., Y. Yingling, G.S. Chirikjian, and B.A. Shapiro. (2006) Structural and dynamical classification of RNA single-base bulges for nanostructure design. J. Comput. Theor. Nanosci. 3:63-77 FEB

Schuyler, A.D., G.S. Chirikjian, J.Q. Lu and H.T. Johnson. (2005) Random-walk statistics in moment-based O(N) tight binding and applications in carbon nanotubes. Phys. Rev. 71(4 Pt 2):046701.

Lee, S., and G.S. Chirikjian. (2005) Pose analysis of alpha-carbons in proteins. Int. J. Robot. Res. 24:183-210.

Lee, S., and G.S. Chirikjian. (2004) Interhelical angle and distance preferences in globular proteins. Biophys. J. 286:1105-17.

Schuyler, A.D., and G.S. Chirikjian. (2004) Normal mode analysis of proteins: a comparison of rigid cluster modes with C(alpha) coarse graining. J. Mol. Graph. Model. 22:183-93.

Kim, M.K., W. Li, B.A. Shapiro, and G.S. Chirikjian. (2003) A comparison between elastic network interpolation and MD simulation of 16S ribosomal RNA. J. Biomol. Struct. Dyn. 21:395-405.

Kim, M.K., R.L. Jernigan, and G.S. Chirikjian. (2003) An elastic network model of HK97 capsid maturation. J. Struct. Biol. 143:107-117.

Kim, M.K., R.L. Jernigan, and G.S. Chirikjian. (2002) Elastic models of conformational transitions in macromolecules. J. Mol. Graph. Model. 21:151-160.

Kim, M.K., R.L. Jernigan, and G.S. Chirikjian. (2002) Efficient generation of feasible pathways for protein conformational transitions. Biophys. J. 83:1620-30.