Research - alphabetical

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PMB Faculty Research

	Mario Amzel Professor and Director, Biophysics & Biophysical Chemistry Structure and mechanism of proteins involved in redox or phosphoryl transfer reactions, such as FPPS, MICAL, and Pl3K-alpha. Many of these proteins studied are targets for drug design.
	Scott Bailey Assistant Professor, Biochemistry & Molecular Biology Structure/function studies of genome integrity
	Doug Barrick Professor, Biophysics Stability and folding of modular proteins, structure and sequence analysis of protein evolution, protein-protein interactions in signaling pathways
	Jürgen Bosch Assistant Professor, Biochemistry & Molecular Biology Structural biology of macromolecular complexes critical for malaria pathogenicity, structure-based drug design
	Greg Bowman Assistant Professor, Biophysics Structural biology of molecular machines involved in nucleosome remodeling
	Ludwig Brand Professor, Biology Protein-ligand interactions, fluorescence spectroscopy of macromolecular complexes
	Greg Chirikjian Professor, Mechanical Engineering Computational mechanics of large proteins, conformational statistics of biological macromolecules, applied mathematics
	Phil Cole Professor, Pharmacology & Molecular Sciences Chemical and biochemical approaches to signal transduction
	Richard Cone Professor, Biophysics Mucosal protection by antibodies
	David Draper Professor & Program Director, Chemistry RNA stability and electrostatics, RNA-protein recognition
	Karen Fleming Associate Professor, Biophysics Membrane protein folding, thermodynamics of protein-protein interactions in membranes, membrane protein modeling
	Bertrand García-Moreno Professor and Chair, Biophysics Experimental and computational studies of protein electrostatics, structure-based energy calculations, ligand-driven conformational transition
	Jeff Gray Associate Professor, Chemical & Biomolecular Engineering Biomolecular modeling, protein-protein docking, protein-surface interactions, allostery, biomineralization
	Rachel Green Professor, Molecular Biology & Genetics Functional analysis of the ribosome using rapid kinetic and spectroscopic approaches
	Marc Greenberg Professor, Chemistry Studies on DNA damage and repair, and their applications
	Blake Hill Associate Professor, Biology NMR studies of protein folding, computational protein design, modeling protein dynamics using NMR spin relaxation data, and structural biology
	Jan Hoh Associate Professor, Physiology Biophysical interactions between biological macromolecules and macromolecular complexes, development of new technology and biomedical applications for scanned probe microscopes
	Kalina Hristova Associate Professor, Materials Science & Engineering Membrane-protein interactions, calculations of 3D membrane structure from 1D xray/neutron scattering profiles, prediction methods for membrane protein topology
	Dan Leahy Professor, Biophysics & Biophysical Chemistry Structural and biophysical characterization of signaling pathways
	Juliette Lecomte Professor, Biophysics Structure and dynamics of proteins in solution by NMR spectroscopy
	Jon Lorsch Professor, Biophysics & Biophysical Chemistry Molecular mechanics of eukaryotic translation
	Roger McMacken Professor, Biochemistry & Molecular Biology Function of multiprotein assemblies, initiation mechanisms for DNA replication, mechanisms of molecular chaperone action
	Al Mildvan Professor, Biological Chemistry NMR studies of enzyme mechanisms (no longer accepting students)
	Paul Miller Professor, Biochemistry & Molecular Biology Nucleic acid chemistry and DNA repair
	Evangelos Moudrianakis Professor, Biology Chromatin structure and function
	Marc Ostermeier Associate Professor, Chemical & Biomolecular Engineering Biomolecular engineering
	Peter Pedersen Professor, Biological Chemistry Cell energetics and its relationship to the diseases cancer and cystic fibrosis
	Sean Prigge Assistant Professor, Molecular Microbiology & Immunology Crystallography of malaria proteins
	Peter Privalov Professor, Biology Thermodynamics of protein folding
	George Rose Professor, Biophysics Theoretical approaches to protein and RNA folding (no longer accepting students)
	Justine Roth Assistant Professor, Chemistry Metalloenzyme catalysis, mechanistic studies of O2 activation and protein damage by reactive oxygen species
	Scheherazade Sadegh-Nasseri Associate Professor, Pathology Mechanisms of T cell activation and unresponsiveness, mechanisms of antigen processing and presentation
	Joel Schildbach Professor, Biology Structural, biochemical, and functional studies of proteins involved in DNA transfer by bacterial conjugation
	Robert Schleif Professor, Biology Mechanism of protein function, particularly regulatory proteins, using genetic, biochemical, biophysical, and computational methods
	David Shortle Professor, Biological Chemistry Protein folding and stability, NMR analysis of denatured protein, prediction of protein structure from sequence
	Jim Stivers Professor, Pharmacology & Molecular Sciences Enzymology of DNA repair and topoisomerases, structure and mechanism by NMR spectroscopy, inhibitor design
	Joel Tolman Assistant Professor, Chemistry Biomolecular recognition, structural genomics, experimental and theoretical NMR
	Craig Townsend Professor, Chemistry Natural product chemistry, enzymology and molecular biology, fatty acid synthase inhibitors for cancer, tuberculosis and obesity
	Herschel Wade Assistant Professor, Biophysics & Biophysical Chemistry Molecular mechanisms of ligand-dependent transcriptional activation-repression, broadly-specific receptor-ligand systems
	Cynthia Wolberger Professor, Biophysics & Biophysical Chemistry Structural studies of transcription regulation, crystallography of transcriptional silencing enzymes, ubiquitin
	Sarah Woodson Professor, Biophysics Folding and dynamics of RNA and RNA-protein complexes
	Tom Woolf Professor, Physiology Computational biophysics of membrane systems, membrane proteins, and protein:lipid interactions; development of new methods for relative free energy and conformational transitions, computational analysis of ligand binding
	Jie Xiao Assistant Professor, Biophysics & Biophysical Chemistry Single molecule and single cell approaches to the molecular biology of the cell
	Jin Zhang Associate Professor, Pharmacology & Molecular Sciences Spatiotemporal regulation of signal transduction

Program in Molecular Biophysics
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Baltimore, MD 21218

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