Class of 2005
nsamara@jhu.edu | B.S. Chemistry, American University of Beirut
Research
Ubiquitination is a post-translational modification that involves the conjugation of the protein ubiquitin to a protein substrate. The conjugation of a K48 linked poly-ubiquitin chain to a lysine residue of a substrate targets it for degradation by the proteosome. However, conjugation of a K63 linked poly-ubiquitin chain to a protein can signal a non-degradative cellular response. My research focuses on proteins involved in the ubiquitination of targets in non-degradative signaling pathways, such as the DNA damage response pathway.
Publications
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